N-Acetyl Semax Amidate (NAS)

What is NAS?

N-Acetyl Semax Amidate (NAS) is a synthetic peptide derived from a natural hormone (ACTH fragment) that has been modified to enhance its stability and effectiveness. It is best known for its neuroprotective, nootropic (cognitive-enhancing), and mood-supporting properties.

NAS has been studied for its ability to improve memory, focus, learning, and resilience to stress, making it particularly relevant for patients seeking both neurological support and cognitive optimization.

Why NAS Therapy?

Patients are often curious about how NAS differs from other brain-boosting treatments. Unlike stimulants, NAS works by:

  • Enhancing brain-derived neurotrophic factor (BDNF), which supports neuroplasticity
    and brain repair
  • Improving cerebral blood flow and oxygen utilization
  • Reducing inflammation and oxidative stress in the nervous system
  • Supporting mood regulation and resilience against anxiety or depression
  • Acting as a neuroprotective agent against long-term brain aging and degeneration

Potential Benefits

Enhanced memory, learning, and cognitive function

Greater mental clarity and focus

Reduced stress, anxiety, and fatigue

Neuroprotection in conditions involving brain injury or degeneration

Support for stroke recovery or neurological disorders

Possible mood enhancement and anti-depressant effects

FAQs

Is it safe?

NAS has been shown to be well tolerated, with very few reported side effects when used appropriately. Treatments are administered under medical supervision to ensure safe dosing
and monitoring.

  • Professionals or students seeking cognitive enhancement.
  • Patients with chronic stress, anxiety, or fatigue
  • Individuals recovering from stroke, brain injury, or neurological conditions
  • Those looking for preventative brain health support and anti-aging benefits
  • Anyone interested in optimizing their mental performance and resilience

NAS is usually given as a nasal spray or subcutaneous injection, depending on the treatment plan.

Some patients notice improved focus and mood within hours to days, while long-term benefits for brain health develop over weeks.

Yes — NAS is often combined with SS-31, NAD+, or other peptides for synergistic effects on brain function, energy, and regeneration.