Skin Booster Treatment

What is Stem Cell Supernatant?

Stem cell supernatant is a cell-free solution derived from carefully cultured stem cells. It is rich in growth factors, cytokines, and regenerative signals that stimulate your skin’s natural repair process. By boosting collagen and elastin production, it helps restore a youthful, radiant complexion.

Why Choose This Treatment?

Patients often ask why stem cell supernatant is different from fillers or Botox. Unlike those treatments, which add volume or temporarily freeze muscles, this therapy works on a cellular level to:

  • Boost collagen and elastin for firmer skin
  • Improve texture and elasticity
  • Reduce fine lines, wrinkles, and sagging
  • Even out skin tone and pigmentation
  • Promote hydration and long-term dermal regeneration
Skin Booster Treatment

Growth Factors Involved

EGF

Epidermal Growth Factor:

Stimulates skin renewal and repair

FGF

Fibroblast Growth Factor:

Promotes collagen and elastin synthesis

VEGF

Vascular Endothelial Growth Factor:

Improves circulation for a natural glow

TGF-β

Transforming Growth Factor Beta:

Balances inflammation and remodeling

IGF

Insulin-Like Growth Factor:

Supports cell growth and structural integrity

Procedure

Step 1.

Consultation

Online or in-person (30–60 minutes, available in English, Japanese, or Chinese).

Step 2.

Treatment

On the same day, the supernatant is injected under local anesthesia into targeted areas of the face. The session takes about 60 minutes.

  • No surgery, no downtime — most patients resume normal activities the same day

Safety & Quality

Produced from healthy Japanese women in their 20s, using ADSCs (adipose-derived stem cells).

  1. Manufactured in a GMP-compliant, ISO Class 1 cleanroom (Facility No. FC319009) under MHLW safety standards.
  2. Rigorously tested for safety: infectious disease screening, sterility and virus testing, harmful substance checks, and skin compatibility testing.
  3. 100% cell-free — only regenerative signals, no live cells.

Results You Can See

Skin Booster Treatment Results Before

Before

Skin Booster Treatment Results After

After

A 52-year-old male’s GAIS score improved from 5 to 3 after three treatments.

Skin Booster Treatment Results Before
Skin Booster Treatment Results After

47-year-old and 30-year-old patients showed clear wrinkle reduction after three sessions (PMID: 37377400, 33073298, 38674316).

FAQs

Results You Can See

Clinical studies have shown visible improvements in skin wrinkles and texture within 3
sessions, with results continuing to build over weeks:

  • Example: A 52-year-old male’s GAIS score improved from 5 to 3 after three treatments.
  • Example: 47-year-old and 30-year-old patients showed clear wrinkle reduction after
    three sessions (PMID: 37377400, 33073298, 38674316).
  • Men and women with fine lines or early wrinkles
  • Those looking for a natural alternative to Botox or fillers
  • Patients with dull, uneven, or dehydrated skin
  • Anyone wanting to slow early signs of aging and rejuvenate their complexion Supernatant for skin

Most patients report minimal discomfort, as local anesthesia is used.

Results typically last several months, with maintenance treatments recommended for continued
improvement.

Yes — because it is cell-free, risks are extremely low compared to cell-based therapies.